Skip to main content
. 2020 Oct 13;13:10361–10372. doi: 10.2147/OTT.S265796

Figure 4.

Figure 4

Enhancement of breast cancer cell proliferation with circ_0003645 sponging miR-139-3p. (A) qRT-PCR experiments detecting miR-139-3p expression with or without inhibiting circ_0003645 or with or without suppressing miR-139-3p in two breast cancer cell lines. (B) CCK-8 analysis shown light absorption values at 450 nm in different time with or without inhibiting circ_0003645 and miR-139-3p in two breast cancer cell lines. (C) Colony formation assay detecting cloning numbers with or without inhibiting circ_0003645 or with or without suppressing miR-139-3p in two breast cancer cell lines. (D) Flow cytometry detecting cell apoptosis levels with or without inhibiting circ_0003645 or with or without suppressing miR-139-3p in two breast cancer cell lines. (E) Western blot analysis showing protein levels changing related with cell apoptosis with or without inhibiting circ_0003645 or with or without suppressing miR-139-3p in two breast cancer cell lines. **P < 0.01, ***P < 0.001, #P < 0.05, ##P < 0.01, ###P < 0.001.