Table 1.
Baseline Characteristics and Comparison Between HA and NonHA Patients
| HA (n=61) | nonHA (n=153) | P | |
|---|---|---|---|
| Preoperative | |||
| Age, median (IQR) year | 55 (49–59) | 55 (47–64) | 0.459 |
| Male. n (%) | 36 (59.0) | 81 (52.9) | 0.420 |
| BMI, median (IQR) kg/m2 | 24.8 (21.7–26.8) | 24.2 (22.4–26.9) | 0.752 |
| Full-time education, median (IQR) year | 9 (9–15) | 9 (6–15) | 0.864 |
| Smoking, n (%) | 15 (24.6) | 17 (11.1) | 0.013 |
| Alcohol abuse, n (%) | 6 (9.8) | 5 (3.3) | 0.049 |
| Poor sleep quality, n (%) | 44 (72.1) | 77 (50.3) | 0.004 |
| Intra- and postoperative | |||
| Duration of surgery, median (IQR) min | 210 (187–260) | 215 (186–260) | 0.569 |
| Duration of anesthesia, median (IQR) min | 255 (225–294) | 260 (230–308) | 0.386 |
| Duration of CPB, median (IQR) min | 101 (82–141) | 108 (88–133) | 0.384 |
| Duration of aortic cross-clamping, median (IQR) min | 76 (57–107) | 78 (65–101) | 0.357 |
| Duration of hypothermia, median (IQR) min | 61 (43–89) | 63 (48–85) | 0.638 |
| Dose of sufentanil, median (IQR) μg/kg/h | 1.12 (0.91–1.50) | 1.02 (0.75–1.39) | 0.032 |
| Volume of intraoperative blood loss, median (IQR) mL | 600 (600–600) | 600 (600–600) | 0.510 |
| Volume of intraoperative non-blood infusion, median (IQR) mL | 600 (450–850) | 600 (400–800) | 0.717 |
| Duration of ventilation with tracheal catheter, median (IQR) min | 934 (735–1170) | 760 (658–1045) | 0.011 |
| ICU length of stay, median (IQR) day | 2 (1–4) | 2 (1–3) | 0.190 |
Abbreviations: HA, hyperalgesia; BMI, body mass index; CPB, cardiopulmonary bypass; ICU, intensive care unit.