FIG 2.

DSCB results for MOMP from sera of female patients with variable clinical outcomes. The numbers of patients selecting peptides at each amino acid of the MOMP at ≥10-fold above the starting library, with experimental patient groups pointing in the positive y axis and virgin controls pointing in the negative y axis, are shown. The yellow shaded region represents the signal sequence of MOMP. The purple shaded regions represent the four variable domains of MOMP (VDI, VDII, VDIII, and VDIV). Labeling: *, a region with nonspecific antibody binding; **, a commonly selected region (CD4/VD3); ***, another commonly selected region, the VD4 conserved region.