FIG 5.

IgG subclasses produced against the VD4 region are the same among patients with different clinical outcomes. The OD₄₅₀ was measured via bait-peptide ELISA to determine anti-VD4 IgG1 (A) and IgG3 (B) antibody responses utilizing patient sera in duplicate. Correlation of IgG and IgG1 (C) and IgG and IgG3 (D) for each patient. A nonparametric Kruskal-Wallis multiple-comparison test was used for ELISA and peak fold change analysis. A nonparametric Spearman test was used for correlation analysis. ****, P < 0.0001.