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Standard HET-CAM Score Used to Evaluate Ocular Tolerance
| S. No. | Effect of Formulation on CAM | Score | Presumption |
|---|---|---|---|
| 1 | No visible hemorrhage | 0 | No irritation |
| 2 | Observable membrane discoloration | 1 | Mild-irritant |
| 3 | Structure cover partially the area of CAM due to membrane discoloration | 2 | Moderate irritant |
| 4 | Structure fully cover the area of CAM due to membrane discoloration | 3 | Severe irritant |
