Table 2.
Characteristics of CML cell lines used in the text
| Cell line | Cell type | BCR-ABL junction type | Derivation | ALDH activity | CD34 | CD38 | CD26 | CD90 |
|---|---|---|---|---|---|---|---|---|
| K562 | BC CML | e14-a2 (b3-a2) | Pleural effusion of a 53-year-old woman with CML in terminal BC [40] | ++ | − | +/− | − | − |
| LAMA-84 | BC CML | e14-a2 (b3-a2) | Peripheral blood of a 29-year-old woman with CML after onset of myeloid-megakaryocytic BC [42] | ++ | − | +/− | − | − |
| KCL22 | BC CML | e13-a2 (b2-a2) | Pleural effusion of a 32-year-old woman with CML [41] | ± | − | +/− | ++ | − |
CML chronic myeloid leukemia, BC blast crisis; ++ high expression, ± low expression, − no expression