Figure 8.

MDPs are self-assembled molecules that allow for the incorporation of multiple ECM derived peptides. (A) Schematic depiction of self assembly of A-B-A block motif peptides into the basic fiber building block of MDPs, adapted from Kumar et al, 2015.^[140] B) Relative levels of pro- and anti-inflammatory cytokines present in dorsal tissues after MDP subcutaneous injection into rats at different time points.^[139] (C) Gross morphometry images of skin wounds were treated with MDP hydrogel (top), IntraSite (middle), and buffer control (bottom). Scale bars are 5mm Adapted from Carrejo et al., 2018.^[126]