Table 4.

Univariate and Multivariate Cox Regression Analysis for OS in HCC Patients with Cirrhosis

	Univariate Cox regression				Multivariate Cox regression
Variables	P-value	HR	95% CI		P-value	HR	95% CI
Risk score (high/low)	0.02	7.11	1.42	35.54	0.01	4.08	1.43	11.68
Age (>60/≤60)	0.02	7.34	1.3	41.57	0.03	2.86	1.09	7.56
BMI	0.21
<25		Reference
≥25		0.48	0.07	3.13
Not reported		25.56	0.37	1750.1
Race	0.26
Non-Asian		Reference
Asian		0.25	0.05	1.31
AFP	0.34
≤20ng/mL		Reference
>20ng/ml		2.8	0.66	11.81
Not reported		0.44	0.01	15.3
Gender(Male/Female)	0.44	2.15	0.3	15.11
Hepatitis B or C	0.1
No		Reference
Yes		0.17	0.03	0.87
Not reported		0.28	0.01	10.28
Alcohol consumption
No	0.12	Reference
Yes		0.12	0.01	1.74
Histologic grade	0.06
G1-2		Reference
G3-4		9.6	1.49	61.93
New tumor event	0.79	0.69	0.05	10.32
Pathologic stage*	0.7
Stage I+II		Reference
Stage III+IV		2.3	0.33	16.02
Cancer status	0.37
Tumor free		Reference
With tumor		2.11	0.12	35.83
Not reported		0.11	0	8.67
Family cancer history	0.25
No		Reference
Yes		3.11	0.46	20.93
Not reported		8.42	0.48	147.11
Residual tumor	0.7
R0		0.66	0.08	5.71
Vascular invasion	0.21
Negative		Reference
Positive		3.61	0.87	14.91

BMI, Body mass index; AFP, Alpha fetoprotein; HR, Hazard ratio; CI, Confidence interval; *TNM staging systems.