Table 6.
Univariate Cox Regression Analysis for RFS in HCC Patients with Cirrhosis
| Variables | P-value | HR | 95% CI | |
|---|---|---|---|---|
| Risk score (high/low) |
0.92 | 0.93 | 0.23 | 3.79 |
| Age(>60/≤60) | 0.11 | 0.33 | 0.08 | 1.3 |
| BMI | 0.94 | |||
| <25 | Reference | |||
| ≥25 | 0.72 | 0.1 | 4.95 | |
| Not reported | 390.28 | 0 | 2.21E+173 | |
| Race | 0.35 | |||
| Non-Asian | Reference | |||
| Asian | 0.22 | 0.03 | 1.68 | |
| Not reported | 23.5 | 0 | 3.52E+226 | |
| AFP | 0.03 | |||
| ≤20ng/mL | Reference | |||
| >20ng/ml | 4.48 | 0.45 | 44.66 | |
| Not reported | 45.46 | 2.18 | 947.68 | |
| Gender (Male/Female) | 0.52 | 2.6 | 0.14 | 47.19 |
| Hepatitis B or C | 0.3 | |||
| No | Reference | |||
| Yes | 0.35 | 0.07 | 1.61 | |
| Not reported | 0.13 | 0.01 | 2.63 | |
| Alcohol consumption (Yes/No) | 0.41 | 0.42 | 0.05 | 3.27 |
| Histologic grade | 0.32 | |||
| G1-2 | Reference | |||
| G3-4 | 5.29 | 0.61 | 45.68 | |
| Not reported | 67.46 | 0 | 1.27E+173 | |
| New tumor event | 0.66 | |||
| No | 152118.71 | 0 | 3.36E+28 | |
| Yes | Reference | |||
| Pathologic stage* | 0.1 | |||
| Stage I+II | Reference | |||
| Stage III+IV | 5.34 | 1.16 | 24.58 | |
| Not reported | 0.27 | 0 | 4.97E+170 | |
| Cancer status | 0.1 | |||
| Tumor free | Reference | |||
| With tumor | 6.89 | 1.17 | 40.49 | |
| Not reported | 1.46 | 0 | . | |
| Family cancer history | 0.23 | |||
| No | Reference | |||
| Yes | 1.21 | 0.09 | 15.49 | |
| Not reported | 0.11 | 0.01 | 1.38 | |
| Residual tumor | 0.71 | 0.58 | 0.04 | 9.56 |
| Vascular invasion | <0.05 | |||
| Negative | Reference | |||
| Positive | 3.4 | 0.59 | 19.61 | |
| Not reported | 0.07 | 0 | 6.845 | |
Note: BMI, Body mass index; AFP, Alpha fetoprotein; HR, Hazard ratio; CI, Confidence interval; *TNM staging systems.