Table 3.
Anti-Hyperglycemic Activity of the Repeated Doses of Solvent Fraction in STZ-Induced Diabetic Mice
| Fasting Blood Glucose Level (mg/dl) | % Reduction | ||||
|---|---|---|---|---|---|
| Group | Baseline | 7th day | 14th day | 7th day | 14th day |
| DC | 342.83±7.23nC | 345.33±7.21nC | 351.33±9.82nC | −0.729 | −2.48 |
| GLC5 mg/kg | 338.33±12.06nC | 147.83±9.56aC, βC, nC | 136.50±5.81aC, βC, nC | 56.31 | 59.66 |
| AQF100 mg/kg | 347.50±9.02 nC | 243.83±7.77aC, βC, nC | 231.83±10.29aC, βC, nC | 29.83 | 33.29 |
| AQF200 mg/kg | 339.50±16.54nC | 220.17±8.78aC, βC, nC | 208.50±13.85aC, βC, nC | 35.15 | 38.59 |
| AQF400 mg/kg | 362.33±13.64nC | 195.00±5.85aC, βC, nC | 171.33±7.83aC, βC, nC | 46.18 | 52.71 |
| NC | 85.83±14.85aC | 87.67±2.69aC | 84.50±2.96 aC | −2.14 | 1.55 |
Notes: Each value represents mean ± SEM; n=6 for each group. aCompared to the diabetic control, ncompared to the normal control, and βcompared to baseline blood glucose level. Cp < 0.001.
Abbreviations: DC, Diabetic control; NC, Normal control; GLC, glibenclamide; AQF, aqueous fraction.