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. 2020 Sep 29;22(3):306–316. doi: 10.5853/jos.2020.01886

Figure 1.

Figure 1.

Web of end-stage renal disease (ESRD), atrial fibrillation (AF), and medications. Aspirin: Although data inconclusive, but it is somewhat in favor of lower risk of stroke and mortality but at increased risk of bleeding. Warfarin: Associated with increased risk of bleeding but inconclusive data on stroke risk reduction and mortality. Apixaban: Mortality with apixaban 5 mg lower as compared to apixaban 2.5 mg and warfarin; risk of bleeding lower with apixaban as compared to warfarin, risk of transient ischemic attack (TIA)/cerebrovascular accident (CVA) possibly lower with apixaban 5 mg as compared to apixaban 2.5 mg but not as compared with warfarin. Increased, Inline graphic; Decreased, Inline graphic; Inconclusive, ☆.