Figure 2.

A male patient aged 47 years with a large solitary hepatocellular carcinoma in V and VIII segment. (A, B) Pretreatment of TACE immediately combined with RFA, the lesion showed heterogeneous low signal on apparent diffusion coefficient map (A) with ADC value of 1.51×10⁻³mm²/s, heterogeneous enhancement (white arrow) in arterial phase (B). (C) Intra-operative digital subtraction angiography showed staining of the large tumor (black arrows). (D) TACE treatment. (E, F) RFA was performed immediately after TACE treatment. (G) Abdominal magnetic resonance imaging performed one month after the combined treatment, the tumor (white arrow) showed complete response. (H) The tumor (white arrow) was well controlled, and no recurrence was found after 12 months follow-up. This patient showed CR at 1month, with progression-free survival of 34.53 months and overall survival of 56.4 months.