Table 4.
Univariate and Multivariate Analysis of Demographic and Imaging Covariates for PFS
| Univariate | P | Multivariate | P | |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Sex | 0.987 (0.376~2.592) | 0.98 | ||
| Age | 0.972 (0.938~1.007) | 0.12 | ||
| Hepatitis B | 1.297 (0.495~3.397) | 0.59 | ||
| Hepatitis C | 0.337 (0.064~1.775) | 0.20 | ||
| AFP | 2.136 (1.024~4.453) | 0.04 | 1.353 (0.622~2.943) | 0.36 |
| Size of tumor | 0.958 (0.853~1.076) | 0.47 | ||
| ADC<1.32x10−3mm2/s | 4.034 (1.927~8.447) | <0.001 | 3.711 (1.705~8.074) | 0.01 |
| PVTT | 1.026 (0.501~2.102) | 0.94 | ||
| Child-Pugh score | 1.706 (0.166~14.373) | 0.99 | ||
| BCLC staging | 1.109 (0.568~2.163) | 0.76 | ||
| ECOG status | 1.049 (0.142~7.778) | 0.96 | ||
| N of TACE+RFA procedures | 0.988(0.775~1.286) | 0.61 | ||
| Fluorouracil | 0.708 (0.306~1.643) | 0.42 | ||
| Adriamycin | 0.771 (0.518~1.148) | 0.20 | ||
| Epirubicin | 1.297 (0.871~1.931) | 0.20 | ||
| Cisplatin | 1.213 (0.500~2.944) | 0.67 |
Abbreviations: ADC, apparent diffusion coefficient; AFP, alpha fetoprotein; BCLC, Barcelona Clinic Liver Cancer; ECOG, Eastern Cooperative Oncology Group.