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. 2020 Oct 14;12:10151–10161. doi: 10.2147/CMAR.S263768

Figure 2.

Figure 2

Hypoxia promotes miR-582-3p expression in NSCLC cells and NSCLC cell-secreted exos. (A) The levels of miR-582-3p in hypoxic and normoxic NSCLC cells was detected using qRT-PCR assay. (B) The levels of miR-582-3p in exos derived from hypoxic NSCLC cells and normoxic NSCLC cells were analyzed by qRT-PCR assay. (C) The levels of miR-582-3p in adjacent normal tissues (n=30) and NSCLC tissues (n=43) were analyzed by qRT-PCR assay. (D) Levels of miR-582-3p in serum exos from healthy donors (n=34) and NSCLC patients (n=43) were detected by qRT-PCR assay. The experiments were repeated three times. Data were expressed as mean±standard deviation. **p<0.01 and ***p<0.001.