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. 2020 Oct 18;9(10):93. doi: 10.1038/s41389-020-00279-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a–f Cell survival of Notch3-silenced (siN3) or Notch1-silenced (siN1) TALL-1 (a, b), Molt3 (c, d) or DND41 (e, f) cells, treated with increasing doses of Tunicamycin compared with control cells CTRL for 24 h. For both Notch3 and Notch1 silencing experiments, left and right panels showed the use of the first (#1) and the second (#2) sequence of siRNA, respectively. Results are shown as the means average deviations of three independent experiments and adjusted P-values of all comparison pairs (CTRL vs siN3/N1 at each single dose) assessed with ANOVA/Sidak’s post-hoc test are shown (i.e., ns not significant; *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001).