Table 1.
TAA in Ovarian cancer.
| Tissue-specific proteins | Overexpressed proteins | Cancer–testis Ags | Altered glycoprotein | NeoAgs |
|---|---|---|---|---|
| EPCAM | HER2/neu | NY-ESO-1 | MUC-1 | TP53 |
| FR-α | MAGE | MUC-2 | ‘private’ NeoAgs | |
| IGFBP-2 | BAGE | MUC-16 (CA125) | ||
| MSLN | LAGE | |||
| GAGE | ||||
| SP17 | ||||
| SSX |
The table shows example of TAA for each category.
BAGE, B melanoma antigen; LAGE, L antigen family member 3; GAGE: G antigen 1; SP17, sperm protein 17; SSX, synovial sarcoma X; TAAs, tumour-associated antigens; EpCAM, epithelial cell adhesion molecule; MAGE-A3, melanoma-associated antigen 3; FR, folate receptor; IGFBP-2, insulin-like growth factor binding protein 2; MSLN, mesothelin.