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. 2020 Sep 26;22:601–614. doi: 10.1016/j.omtn.2020.09.026

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© 2020 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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MSC-Exosomes Inhibited Apoptosis and Calcification in EPCs

(A) Anti-apoptosis of MSC-exosomes in TBHP-treated EPCs. (B) Capase-3, caspase-7, and caspase-9 in EPCs after treatment of MSC-exosomes. (C) Alizarin red staining and ALP staining of EPCs after treatment of MSC-exosomes (scale bars, 50 μm). (D) Runx2, BMP-2, and Sox9 in EPCs after treatment of MSC-exosomes. (E) Immunofluorescence of Runx2 protein in EPCs after treatment of MSC-exosomes (scale bars, 200 μm). Data are mean ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.