Fig. 5.

(a) Reconstructed 3D volume of PA data of mouse lower abdomen at GD 17 before injection of FA-PEG-ICG at 740 nm. (b, c) 3D volume of PA data at t=5 min and t=90 min post injection, respectively. Accumulation of FA-PEG-ICG were colored green. Here the placenta (p) and spiral artery (sa) are labeled. (d) Plot of normalized photoacoustic signal intensity of pre and post injection of segmented placentas (n = 3) versus time for 90 min time period. Here post injection PA signal intensity is normalized by pre-injection PA signal intensity of each placenta. The PA signal started increasing 30 min of post injection. Scale bar is 3 mm. Videos of the reconstructed 3D volumes of the PA images are provided in the Supplementary.