Table 2.
. Hematological parameters of non-pregnant female Wistar rats exposed to extracts (dose 2000 mg/kg) on14th day follow up.
| Hematological Parameters | Normal control | Cm | Ra | Ap | Sp | Aa |
|---|---|---|---|---|---|---|
| WBC (Cell x 103/mm3) | 6.69 + 1.21 | 5.44 + 1.23 | 6.10 + 2.67 | 5.99 + 0.31 | 6.12 + 1.47 | 6.67 + 0.91 |
| RBC (Cell x 106/mm3) | 4.75 + 0.40 | 4.46 + 0.67 | 4.52 + 1.39 | 4.55 + 0.28 | 5.00 + 0.16 | 4.94 + 0.53 |
| HGB (g/dl) | 18.23 + 1.00 | 13.11 + 1.31** | 14.10 + 2.52* | 16.25 + 1.20 | 17.36 + 0.20 | 17.36 + 1.06 |
| HCT (%) | 48.23 + 3.37 | 44.80 + 4.03 | 43.46 + 7.33 | 46.65 + 2.75 | 50.50 + 0.43 | 50.46 + 2.68 |
| MCV (fl/cell) | 56.36 + 1.25 | 57.33 + 1.07 | 56.50 + 1.21 | 54.50 + 1.41 | 56.13 + 1.43 | 56.46 + 0.61 |
| MCH (pg/cell) | 19.43 + 0.25 | 19.20 + 0.34 | 19.03 + 0.20 | 18.95 + 0.77 | 19.26 + 0.49 | 19.43 + 0.40 |
| MCHC (g/dl) | 34.50 + 0.30 | 33.40 + 0.10 | 33.63 + 0.32 | 34.85 + 0.49 | 34.36 + 0.25 | 34.40 + 0.43 |
| RDW-SD (fl) | 28.96 + 2.80 | 27.76 + 0.60 | 27.60 + 1.67 | 26.95 + 0.63 | 27.93 + 1.25 | 28.20 + 0.85 |
| RDW-CV(%) | 17.53 + 1.49 | 15.06 + 1.19 | 15.76 + 2.56 | 17.20 + 1.13 | 18.43 + 0.20 | 17.33 + 1.58 |
| PDW (fl) | 8.70 + 0.20 | 8.53 + 0.45 | 8.73 + 0.25 | 8.30 + 0.28 | 9.06 + 0.32 | 8.80 + 0.30 |
| MPV (fl) | 8.00 + 0.20 | 7.96 + 0.35 | 7.90 + 0.34 | 7.55 + 21.21 | 8.06 + 0.23 | 7.90 + 0.30 |
| P-LCR (%) | 10.83 + 1.20 | 10.13 + 2.41 | 10.06 + 2.40 | 8.40 + 1.41 | 11.14 + 1.70 | 10.33 + 1.70 |
| PCT (ng/mL) | 0.67 + 0.13 | 0.35 + 0.14 | 0.43 + 0.31 | 0.75 + 0.03 | 0.35 + 0.11 | 0.63 + 0.17 |
| NEUT (%) | 0.83 + 0.08 | 0.73 + 0.02 | 0.70 + 0.27 | 0.78 + 0.26 | 0.84 + 0.18 | 1.06 + 0.26 |
| LYM (%) | 5.39 + 0.98 | 4.09 + 1.00 | 5.08 + 2.29 | 5.01 + 0.69 | 4.83 + 1.05 | 5.15 + 0.84 |
| MONO (103/mL) | 0.17 + 0.17 | 0.12 + 0.05 | 0.20 + 0.16 | 0.14 + 0.14 | 0.24 + 0.13 | 0.22 + 0.05 |
| EO(x103/mL) | 0.08 + 0.00 | 0.06 + 0.00 | 0.06 + 0.01 | 0.05 + 0.02 | 0.19 + 0.05 | 0.08 + 0.02 |
Note: WBC = White Blood Cells; RBC = Red Blood Cells; HGB =Hemoglobin; HCT = Hematocrit (called Packed Cell Volume, PCV); MCV = Mean Corpuscular Volume; MCH = Mean Corpuscular Hemoglobin; MCHC = Mean Corpuscular Hemoglobin Concentration; RDW-SD = Standard Deviation in Red Cell Distribution Width; RDW-CV = Coefficient of Variation in Red Cell Distribution Width; PDW = Platelet Distribution Width; MPV = Mean Platelet Volume; PLT = Platelet; P-LCR = Platelet Larger Cell Ratio; PCT = Procalcitonin; NEUT = Neutrophils; LYM = Lymphocyte Count; MONO = Monocytes; EO= Eosinophils; pg(pictograms); Cm=C. murale leaves; Ra=R. abyssinicus rhizome; Ap=A. pulcherrima gel; Sp= S. punctata aerial parts, and Aa=A. aspera leaves. Values are represented as mean + SD of triplicates (n = 3). *p < 0.05, **p < 0.01,***p < 0.001 indicate significant changes in comparison with the normal control.