Antibiotic release profiles from MgAl-CFX and ZrP-GTM copolymer composites under different eluent conditions. Cumulative release of (A) CFX from MgAl-CFX_s and (B) GTM from ZrP-GTM_s immersed in dPBS during 4 weeks at 37 °C, proving the filler-antibiotic concentration dependent release. Influence of filler presence and pH of the eluent solution on the cumulative release percentage of (C) CFX and (D) GTM from filler-antibiotic composite films (20% MgAl-CFX_f and 20% ZrP-GTM_f, respectively) and films composed of comparable amounts of antibiotic directly dispersed in the copolymer matrix (10% CFX_f and 10% GTM_f), immersed in buffers at acidic, neutral and basic pH during 3 weeks at 37 °C. Influence of the ionic concentration of the eluent solution on the cumulative release percentage of (E) CFX and (F) GTM from 20% MgAl-CFX_f and 20% ZrP-GTM_f, respectively, during 3 weeks a 37 °C.