Fig. 6.
Effect of TRPV3 overexpression on ERS-associated cell cycle arrest. Cell cycle analysis by flow cytometry on BEAS-2B cells (A) or TRPV3OE cells (B), after 4 hours treatment with either vehicle (white bars), thapsigargin (Thaps.; 1 μM; black bars), or pine WSPM (5 μg/cm2; gray bars). The data represent cells in a specific phase of the cell cycle as a percentage of total viable cells. Data are presented as means ± S.D. from n = 3 replicates. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. Statistical significance was determined using an ordinary two-way ANOVA with the Bonferonni correction.