Table 5.
Diagnostic performance expressed as areas under the ROC curve [AUROC, 95 % confidence intervals (CI)], and threshold observed to maximize the sensitivity and specificity determined by ROC analysis to assess the utility of each measure for the detection of mucosal healing. Only significant parameters are listed.
| AUROC | CI | p | Threshold | Sensitivity (%) | Specificity (%) | TP | TN | FP | FN | Accuracy (%) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wall thickness post-treatment (mean ± SD, mm) | 0.938 | 0.840-1.000 | 0.001 | <6.5 | 73.3 | 100.0 | 9/24 (37.5) |
11/24 (45.8) |
4/24 (16.7) |
0/24 (0) |
83.3 |
| MaRIA post-treatment (mean ± SD) |
0.901 | 0.766-1.000 | 0.004 | <17.99 | 77 | 100 | 8/21 (38.1) |
10/21 (47.6) |
3/21 (14.3) |
0/21 (0) |
85.7 |
| Δ MaRIA (%, mean ± SD) | 0.813 | 0.602-1.000 | 0.024 | <-24.78 | 77 | 71.4 | 7/21 (33.3) |
3/21 (14.3) |
10/21 (47.6) |
1/21 (4.8) |
50 |
| Clermont pre-treatment (mean ± SD) |
0.835 | 0.659-1.000 | 0.016 | <24.02 | 69.2 | 100 | 8/23 (34.8) |
9/23 (39.1) |
6/23 (26.1) |
0 (0) |
73.9 |
| Clermont post-treatment (mean ± SD) |
0.912 | 0.773-1.000 | 0.003 | <9.41 | 100 | 71.4 | 6/23 (26.1) |
15/23 (65.2) |
0/23 (0) |
2/23 (8.7) |
91.3 |
TP: true positive rate; TN: true negative rate; FP: false positive rate; FN: false negative rate, expressed as proportion of patients (percentage).