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. 2020 Oct 10;2020:8493916. doi: 10.1155/2020/8493916

Table 3.

Incident rate and hazard ratio for dementia with PD.

Group Without PD With PD Crude HR (95% CI) p Adjusted HRb (95% CI) p
Incident ratea Incident ratea
Overall 8.3 24.2 2.91 (2.39–3.53) <0.001 3.05 (2.51–3.70) <0.001
Female 7.9 22.5 2.87 (2.16–3.82) <0.001 2.92 (2.19–3.89) <0.001
Male 8.7 25.8 2.94 (2.26–3.83) <0.001 3.20 (2.45–4.17) <0.001
Age, years
 <50 0.2 2.5 10.14 (1.97–52.26) 0.006 12.10 (2.15–68.04) 0.005
 50–64 1.3 13.1 9.84 (4.51–21.49) <0.001 9.59 (4.38–20.98) <0.001
 ≧65 15.4 42.3 2.78 (2.26–3.42) <0.001 2.74 (2.22–3.36) <0.001
Depression
 Noc 7.9 29.2 3.71 (3.00–4.58) <0.001 3.30 (2.67–4.07) <0.001
 Yesc 13.7 13.2 0.97 (0.58–1.61) 0.905 1.77 (1.06–2.96) 0.030

Note. PD = Parkinson's disease, HR = hazard ratio, CI = confidence interval, n = case number, % = percentage, and p = p value. aPer 1000 person-years. bAdjusted HR: adjusted for age, gender, hypertension, diabetes mellitus, hyperlipidemia, and ischemic heart disease. c“No” = without depression; “yes” = with depression.