| Covariates | HR (95% CI) | p-value |
| Full-dose group | 0.16 (0.03-0.85) | 0.03 |
| Reduced-dose group | 0.41 (0.14-1.21) | 0.11 |
| Age | 1.01 (0.94-1.07) | 0.87 |
| Male Gender | 1.76 (0.37-8.31) | 0.47 |
| Smoke exposure | 0.92 (0.33-2.58) | 0.88 |
| Number of comorbidities | 0.45 (0.21-0.95) | 0.04 |
| Presence of pulmonary hypertension | 0.37 (0.07-1.88) | 0.23 |
| % predicted FVC at start of dose | 0.97 (0.94-0.99) | 0.03 |