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. 2020 Jun 30;37(2):148–157. doi: 10.36141/svdld.v37i2.8718

Table 3.

Adverse drug reactions on pirfenidone treatment (n = 115)

Adverse drug reaction Number (percentage)
Any adverse drug reaction 96 (83.5)
Anorexia 48 (41.7)
Dyspepsia 34 (29.6)
Nausea 22 (19.1)
Uneasiness 20 (17.4)
Rash 20 (17.4)
Weight loss 17 (14.8)
Itching 16 (13.9)
Insomnia 16 (13.9)
Giddiness 13 (11.3)
Flushing 9 (7.8)
Raised liver transaminases 8 (7.0)
Vomiting 8 (7.0)
Dry mouth 7 (6.1)
Others* 25 (21.7)

*Other adverse drug reactions each with a frequency of < 5% included abdominal pain, chest congestion, constipation, diarrhea, drowsiness, fatigue, forgetfulness, headache, hoarseness of voice, increased cough, irritability, mucositis, nasopharyngitis, numbness, paraesthesia, slurred speech, somnolence, and vertigo.