Table 2.
Correlation among circulating biomarkers of calcification, phosphorus homeostasis, and inflammation and procalcification factors in adults initiating hemodialysis
| Variable | Correlations |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| dp-ucMGP | OPG | Fetuin A | FGF23 | Klotho | Corrected Ca | Phosphate | PTH | CRP | Albumin | |
| dp-ucMGP | 1.00 | |||||||||
| OPG | 0.01 | 1.00 | ||||||||
| Fetuin-A | −0.13a | −0.06 | 1.00 | |||||||
| FGF23 | 0.12a | 0.10 | −0.03 | 1.00 | ||||||
| Klotho | 0.00 | 0.06 | 0.02 | 0.04 | 1.00 | |||||
| Corrected Ca | −0.00 | 0.04 | 0.04 | 0.12a | −0.00 | 1.00 | ||||
| Phosphate | 0.05 | 0.04 | 0.09 | 0.35a | −0.10 | −0.20a | 1.00 | |||
| PTH | −0.13a | −0.03 | −0.02 | 0.23a | 0.06 | −0.27a | 0.22a | 1.00 | ||
| CRP | 0.25a | 0.03 | −0.19a | 0.05 | 0.05 | −0.00 | 0.00 | 0.02 | 1.00 | |
| Albumin | −0.10 | −0.23a | 0.20a | −0.12a | −0.09 | −0.05 | 0.03 | 0.13a | −0.05 | 1.00 |
CRP, C-reactive protein; dp-ucMGP, desphospho-uncarboxylated matrix Gla protein; FGF23, fibroblast growth factor 23; HR, hazard ratio; OPG, osteoprotegerin; PTH, parathyroid hormone.
a
P < 0.05 (statistically significant).