Figure 2.

Changes in biomarkers during active and inactive periods. Periods of active disease leading to a remission (blue lines) or without a remission (red lines) and inactive episodes (green lines) are illustrated at 3 different time points: T1, the first measurement; T3, the last measurement; and T2, the average of all measurements in between. We show the percentage reduction in proteinuria and sC5b-9. AAV, anti-neutrophil cytoplasmic autoantibody–associated vasculitis; FSGS, focal and segmental glomerulosclerosis; IgAN, IgA nephropathy; LN, lupus nephritis; MCP-1, monocyte chemoattractant protein–1; MN, membranous nephropathy; MPGN, membranoproliferative glomerulonephritis; TGF-β1, transforming growth factor beta 1.