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. 2020 Oct 13;18(10):865–876. doi: 10.18502/ijrm.v13i10.7771

Table 5.

Effects of licorice extract on the germinal vesicles (GV), metaphase 2 (MII), fertilization rate, 2-cell stage, and blastocysts in PCOS-induced mice


Groups GV follicles MII oocytes Fertilized oocytes 2-cell stage Blastocyst
Group I 50 82.00 ± 2.82 85.50 ± 2.12 78.50 ± 3.53 64.50 ± 3.53
Group II 40a*** 65.50 ± 3.53a* 56.50 ± 2.12a*** 68.00 ± 1.41 41.00 ± 2.82a**
Group III 47 76.50 ± 3.53 78.00 ± 2.82b*** 71.50 ± 2.12 55.50 ± 2.12
Group IV 42a* 78.50 ± 2.12 87.50 ± 0.70b*** 78.00 ± 4.24 62.00 ± 4.24
Data presented as Mean ± SD. one-way ANOVA test, *, **, *** Significant difference between the PCOS and other groups at p < 0.05, p < 0.01, and p < 0.001 level respectively. aSignificant difference compared to the control group; bSignificant difference compared to the PCOS group