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. 2020 Oct 13;18(10):885–898. doi: 10.18502/ijrm.v13i10.7773

Table 2.

Rate of polyploidy, chaotic, and total chromosomal abnormalities in hAFCs following long-term cultures and under two different mediums using the FISH technique and regarding 8 chromosomes


Unpaired t test
Chromosomal abnormality DMEM medium (n = 535) Amnio MAX medium (n = 510) 95% CI of difference P-value
Polyploidy 5.01 ± 5.22 1.75 ± 2.62 (-0.08, 6.61) 0.056
Chaotic 0.99 ± 1.70 0 (0.02, 1.97) 0.04
Total 9.57 ± 8.11 4.32 ± 3.33 (0.23, 10.26) 0.04
Data presented as Mean ± SD. Student's t test Chr: Chromosome; DMEM: Dulbecco's modified eagle medium; Amnio MAX: AmnioMAX II complete medium