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. Author manuscript; available in PMC: 2020 Oct 19.
Published in final edited form as: Science. 2020 Aug 14;369(6505):799–806. doi: 10.1126/science.abb8271

Figure 1.

Figure 1.

A. Selected examples of oxidized ent-kauranes, ent-atisanes and ent-trachylobanes. B. Limitations of purely chemical C–H oxidation approaches in steviol-based semisynthesis. C. Retrosynthetic analysis of oxidized ent-kauranes, ent-atisanes and ent-trachylobanes employing a hybrid oxidative approach that combines chemical and enzymatic C–H oxidations. Glc = β-D-glucopyranosyl.