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. 2020 Aug 19;11(9):787. doi: 10.3390/mi11090787

Figure 2.

Figure 2

Schematic diagrams of the blood–brain barrier mimicking microfluidic chip. (A) Cellular constituents of the neuro vascular unit (NVU). Adapted from Reference [75]; (B) sandwiched dynamic model. Reproduced with permission from The Royal Society of Chemistry [79]; (C) dynamic model/barrier function. Adapted from Reference [86]; (D) dynamic two-chamber model/transport function. Reproduced with permission from The Royal Society of Chemistry [88]; (E) in vitro NVU model/cell–cell communication and drug screening. Adapted from Reference [89]; (F) 3D co-culture model/barrier and transport function. Reproduced with permission from ACS publications [92]; (G) 3D printing model/barrier function analysis. Adapted from Reference [93]; (H) Neuropathological analysis/drug screening. Reproduced with permission from Springer Nature [94].