Table 1.
Days | Control | CP | Propolis | NP-10 | CP + Propolis | CP + NP-10 | CP + NP-30 | p | |
---|---|---|---|---|---|---|---|---|---|
BW | IW | 246.60 ± 3.94 | 247.75 ± 3.18 | 247.63 ± 13.42 | 245.33 ± 3.96 | 247.00 ± 1.48 | 243.93 ± 3.88 | 247.00 ± 3.63 | NS |
7. | 273.50 ± 8.75 | 260.44 ± 2.17 | 275.63 ± 13.09 | 270.67 ± 1.86 | 264.60 ± 4.56 | 260.36 ± 3.60 | 261.25 ± 3.32 | NS | |
14. | 291.30 ± 3.52 a,b | 272.44 ± 3.63 c | 295.25 ± 3.40 a | 299.08 ± 2.96 a | 280.20 ± 9.29 b,c | 276.64 ± 2.97 c | 277.50 ± 4.32 b,c | ** | |
21. | 312.80 ± 1.69 a | 288.81 ± 2.38 b | 314.25 ± 13.21 a | 314.08 ± 4.67 a | 310.70 ± 10.26 a | 290.50 ± 3.90 b | 294.81 ± 6.42 a,b | ** | |
BWC | 1–7 | 3.84 ± 1.10 | 1.81 ± 0.29 | 4.00 ± 0.50 | 3.62 ± 0.66 | 2.52 ± 0.68 | 2.35 ± 0.35 | 2.04 ± 0.50 | NS |
8–14 | 2.54 ± 0.98 | 1.72 ± 0.40 | 2.80 ± 1.41 | 4.06 ± 0.62 | 2.23 ± 0.97 | 2.33 ± 0.50 | 2.32 ± 0.52 | NS | |
15–21 | 3.07 ± 0.52 | 2.34 ± 0.54 | 2.72 ± 1.49 | 2.14 ± 0.66 | 4.36 ± 1.17 | 1.98 ± 0.47 | 2.48 ± 0.76 | NS | |
1–21 | 3.15 ± 0.25 a,b | 1.95 ± 0.21 c | 3.18 ± 0.31 a,b | 3.28 ± 0.34 a | 3.03 ± 0.47 a,b | 2.22 ± 0.21 b,c | 2.28 ± 0.30 b,c | ** | |
FI | 1–7 | 19.87 ± 0.86 | 19.59 ± 0.86 | 20.76 ± 0.47 | 19.89 ± 0.67 | 19.64 ± 1.08 | 19.33 ± 1.40 | 20.18 ± 0.91 | NS |
8–14 | 22.80 ± 0.52 | 19.67 ± 1.23 | 19.30 ± 0.36 | 22.00 ± 1.00 | 19.52 ± 0.75 | 19.14 ± 0.89 | 20.89 ± 1.23 | NS | |
15–21 | 24.50 ± 0.49 a | 20.49 ± 0.32 c | 23.87 ± 0.11 a,b | 23.70 ± 1.11 a,b | 23.64 ± 1.35 a,b | 22.07 ± 0.46 b,c | 23.81 ± 0.75 a,b | ** | |
1–21 | 22.39 ± 0.13 a | 19.92 ± 0.39 c | 21.31 ± 0.24 a,b,c | 21.87 ± 0.71 a,b | 20.93 ± 0.63 a,b,c | 20.18 ± 0.50 b,c | 21.63 ± 0.78 a,b,c | * |
IW: Initial weight; CP: cisplatin; NP-10: 10 mg/kg BW of nano-propolis; NP-30: 30 mg/kg body weight of nano-propolis; a,b,c: Mean values with different superscripts within a row differ significantly; NS: non-significant; *: p < 0.05; **: p < 0.01.