Figure 4.

Gene- and variant-specific survival of mice exposed to FA or O₃ prior to K. pneumoniae infection. Panel (A) depicts differences in daily survival of male and female mice carrying a single SP-A1 or SP-A2 variant and those lacking SP-A (KO). Panel (B) depicts differences in daily survival of KO and each SP-A1 (6A², 6A⁴) variant, and Panel (C) depicts differences in survival of KO and each SP-A2 (1A⁰, 1A³) variant. In all panels, males and females are combined after FA or O₃ exposure and infection. Significant differences are indicated for survival * p < 0.05 (log-rank test and one-way analysis of variance (ANOVA) followed by Bonferroni multiple comparisons correction).