AMDIS	automated mass spectral deconvolution and identification system
BC	bladder cancer
cv	coefficient of variation
DDA	data-dependent acquisition
tDDA	target-direct data-dependent acquisition
tsDDA	time staggered-direct data-dependent acquisition
DITQM	data independent targeted quantitative metabolomics
EIC	extracted ions current
ESI	electrospray ionization quadrupole
GC	gas chromatography
GC-MS	gas chromatography coupled with mass spectrometry
GOT	globally optimized targeted method
dGOT	database-assisted globally optimized targeted method
ts/msGOT	time staggered/mass staggered globally optimized targeted method
GPF	gas-phase fractionation method
HCC	hepatocellular carcinoma
HMDB	human metabolome database
HPLC	high-performance liquid chromatography
UHPLC	Ulrta-high performance liquid chromatography
HPLC-MS	high-performance liquid chromatography coupled with mass spectrometry
HRMS	high resolution mass spectrometers
IDA	information dependent acquisition
LRMS	low resolution mass spectrometers
MIM	multiple ion monitoring
tsMIM	time staggered-multiple ion monitoring
MRM	multiple reaction monitoring
MS	mass spectrometry
NMR	nuclear magnetic resonance
Q-Orbitrap	quadrupole-orbitrap
Q-TOF	quadrupole time-of-flight
QC	quality control
QQQ MS	triple quadrupole mass spectrometry
QTrap	quadrupole trap
RSD	Relative Standard Deviation
RT	retention time
RTL	the retention time locking
SESI	secondary electrospray ionization
SIM	selected ion monitoring
SRM	selected reaction monitoring
SWATH	sequential windowed acquisition of all theoretical fragment ion
TIC	total ion current
TOF	time of flight