Table 2.
Overall population (n=54) |
Cohort-1 (n=27) |
Cohort-2 (n=27) |
|
Confirmed objective response, n(%) | 15 (27.8%) | 9 (33.3%) | 6 (22.2%) |
Complete response | 2 (3.7%) | 1 (3.7%) | 1 (3.7%) |
Partial response | 13 (24.1%) | 8 (29.6%) | 5 (18.5%) |
Stable disease, n(%) | 15 (27.8%) | 8 (29.6%) | 7 (25.9%) |
Progressive disease, n(%) | 24 (44.4%) | 10 (37.0%) | 14 (51.9%) |
Disease control rate, n(%) | 30 (55.6%) | 17 (63.0%) | 13 (48.1%) |
Median duration of response, weeks | 18.0 (range 6.0–83.1) |
17.9 (range 6.0–83.1) |
19.0 (range 8.0–38.0) |
Median time to response, weeks | 6.0 (range 4.7–18.0) | 6.0 (range 5.1–18.0) | 5.9 (range 4.7–8.0) |
iRANO, immunotherapy response assessment for neuro-oncology.