Figure 5.
Endocytosis of sphere and prolate-shaped ellipsoids with different aspect ratios. (a) The rotation of the nanoparticle (αz); (b) The number of ligand-receptor bonds; (c) The normalized CCP area ratio RCCP; and (d) The total energy of the system U as a function of MC steps during CME. The equilibrium particle-membrane profiles for ellipsoid with (e) AR = 0.90, (f) AR = 0.67, (g) AR = 0.42 and (h) AR = 0.25. The CCP (pink region), bonded TfR (red dots), free TfR (black dots), bonded Tf (green dots) and unbonded Tf (blue dots) are all shown in the profiles.