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Two entry modes of the prolate ellipsoid with AR = 0.67. (a) The number of ligand-receptor bonds; (b) The rotation of the particle (αz); (c) The total energy of the system U as a function of MC steps during CME. (d-e) The membrane-particle profiles at different stages identified in (a). The CCP (pink region), bonded TfR (red dots), free TfR (black dots), bonded Tf (green dots) and unbonded Tf (blue dots) are all shown in the profiles.
