Table 2.
Represents the encapsulation and loading efficiency of nanoparticles. Data are shown as mean ± SD (n = 3).
| S.No. | Formulations | Ratio EPI: PTX |
% Encapsulation Efficiency | % Loading Efficiency | ||
|---|---|---|---|---|---|---|
| Epirubicin | Paclitaxel | Epirubicin | Paclitaxel | |||
| 1 | PLGA-EPI NPs | - | 74.09 ± 0.42 | - | 9.56 ± 0.11 | - |
| 2 | PLGA-PTX NPs | - | - | 90.88 ± 1.73 | - | 10.88 ± 0.67 |
| 3 | PLGA-PEI-EPI-PTX-NPs | 1:5 | 74.89 ± 5.92 | 87.25 ± 5.67 | 9.58 ± 3.56 | 6.99 ± 1.24 |
| 4 | PLGA-PEI-EPI-PTX-NPs | 1:3 | 67.75 ± 0.41 | 77.05 ± 8.80 | 6.99 ± 1.54 | 7.95 ± 3.32 |
| 5 | PLGA-PEI-EPI-PTX-NPs | 1:1 | 77.34 ± 2.99 | 84.61 ± 0.13 | 5.35 ± 2.19 | 7.26 ± 0.33 |
| 6 | PLGA-PEI-EPI-PTX-NPs | 3:1 | 57.27 ± 2.43 | 75.20 ± 0.86 | 4.92 ± 0.27 | 3.31 ± 0.40 |
| 7 | PLGA-PEI-EPI-PTX-NPs | 5:1 | 59.66 ± 5.28 | 62.94 ± 8.0 | 5.61 ± 1.02 | 2.11 ± 0.12 |