| 5-ASA | 5-aminosalicylic acid |
| 5-HT | serotonin |
| AA | arachidonic acid |
| ALA | α-linolenic acid |
| Akt | protein kinase B |
| APC | adenomatous polyposis coli |
| BMMCs | bone marrow-derived mast cells |
| C2 | canine mastocytoma cell line |
| CCL | C-C motif chemokine ligand |
| CD | Crohn’s disease |
| CNS | central nervous system |
| COX | cyclooxygenase |
| CRF | corticotropin releasing factor |
| CXCL | Chemokine (C-X-C motif) ligand |
| CXCR2 | chemokine (C-X-C motif) ligand 2 (Interleukin 8 receptor beta) |
| DHA | docosahexaenoic acid |
| DNFB | dinitrofluorobenzene |
| DRG | dorsal root ganglia |
| DSCG | disodium cromoglicate |
| EGCG | epigallocatechin-3-gallate |
| ENS | enteric nervous system |
| EPA | eicosapentaenoic acid |
| ERK | extracellular signal-regulated kinase |
| ET-1 | endothelin 1 |
| FcεRI | high-affinity IgE receptor |
| FGF | fibroblast growth factor |
| FODMAPs | fermentable oligosaccharides, disaccharides, monosaccharides and polyols |
| GATA-1 | GATA binding protein-1 |
| GATA-2 | GATA binding protein-2 |
| GI | gastrointestinal |
| GLA | γ-linolenic acid |
| GM-CSF | granulocyte macrophage colony-stimulating factor |
| IBD | inflammatory bowel disease |
| IBS | irritable bowel syndrome |
| IBS-C | IBS with predominant constipation |
| IBS-D | IBS with predominant diarrhea |
| IBS-M | mixed IBS |
| IBS-U | unclassified IBS |
| IFN | interferon |
| Ig | immunoglobulin |
| IL | interleukin |
| IP3 | inositol-1,4,5-triphosphate |
| JAM | junctional adhesion molecule |
| JNK | c-Jun NH2–terminal kinase |
| LIF | leukemia inhibitory factor |
| LPS | lipopolysaccharide |
| LT | leukotriene |
| MAPK | mitogen-activated protein kinase |
| MBP | eosinophil major basic protein |
| MC-CPA | carboxypeptidase A3 |
| MCP | monocyte chemotactic protein |
| MIP | macrophage inflammatory protein |
| MMP | matrix metalloproteinase |
| MMP9 | matrix metallopeptidase 9 |
| MRGPRX2 | MAS-related G-protein-coupled receptor X2 |
| MS | maternal separation test |
| MyD88 | myeloid differentiation primary response 88 |
| NFκβ | nuclear factor κβ |
| NGF | nerve growth factor |
| NK | natural killer |
| NO | nitric oxide |
| PAF | platelet activating factor |
| PAMP | pathogen-associated molecular pattern |
| PDGF | platelet-derived growth factor |
| PG | prostaglandin |
| PI-IBS | post-infectious IBS |
| PI3K-Akt | phosphoinositide 3-OH kinase-protein kinase B |
| PKC | protein kinase C |
| PKC θ | calcium-insensitive protein kinase C theta |
| PLCγ1 | phosphoinositide-specific phospholipase C |
| pp125 (FAK) | focal adhesion kinase |
| PPARγ | peroxisome proliferator-activated receptor γ |
| PUFA | polyunsaturated fatty acid |
| RANTES | regulated upon activation, normal T cell expressed and secreted |
| RBL | Rat basophilic leukemia |
| RBL-2H3 | rat basophilic leukemia mast cell line |
| ROS | reactive oxygen species |
| S1P1 | sphingosine-1-phosphate (S1P) receptor 1 |
| S1P2 | sphingosine-1-phosphate (S1P) receptor 2 |
| SCF | stem cell factor |
| SCFA | short chain fatty acid |
| SOC | store-operated Ca2+ channels |
| SP | substance P |
| SphK | sphingosine kinase |
| SyK | tyrosine-protein kinase SYK or spleen tyrosine kinase |
| TGF | transforming growth factor |
| TLR | toll-like receptors |
| TNF | tumor necrosis factor |
| Treg | regulatory T cells |
| VCAM-1 | vascular cell adhesion molecule 1 |
| VEGF | vascular endothelial growth factor |
| VIP | vasoactive intestinal peptide |
| VDR | vitamin D receptor |
| WRS | wrap restraint stress |