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. 2020 Sep 7;25(18):4089. doi: 10.3390/molecules25184089

Figure 6.

Figure 6

Effect of SNAH on MAPK and p65 signaling pathways. (a) The time course of ERK (extracellular-signal-regulated kinase) and SAPK/JNK (Stress-activated protein kinase/Jun-amino-terminal kinase) phosphorylation stimulated by LPS in RAW264.7 cells. (b) RAW 264.7 cells were treated for 15 min with LPS (1 μg/mL) alone or with LPS (1 μg/mL) coupled with 3–100 μM SNAH. Cell lysates were prepared and blotted with the indicated anti-phospho-antibodies. Total ERK1/2, SAPK/JNK, and NF-κB (p65) were probed as quantitative controls.