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. 2020 Sep 11;25(18):4170. doi: 10.3390/molecules25184170

Table 4.

The factors and factor level setting of the Box–Behnken design (BBD).

Coding Level Pressure (X1, MPa) Flow (X2, L/h) Temperature (X3, °C) Time (X4, min)
−1 15 50 32 30
0 25 75 47 90
+1 35 100 62 150