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. 2020 Sep 12;25(18):4181. doi: 10.3390/molecules25184181

Table 4.

Effect of test compounds on the in vitro proliferation of L. amazonensis and L. chagasi promastigotes.

Compounds IC50 (µM)
L. amazonensis 		IC50 (µM)
L. chagasi
ICaf 1.56
(1.35–1.73)		 1.71
(1.46–1.88)
ICaf:β-CD (CO, 1:1) 2.74
(2.33–2.91)		 1.95
(1.64–2.11)
β-CD 88.10
(67.21–95.6)		 88.10
(67.21–95.6)
Miltefosine 6.69
(5.74–8.04)		 6.38
(4.85–7.94)

Data are presented as IC50 values (µM) and their 95% confidence interval obtained by non-linear regression from three independent experiments performed in triplicate, measured by viable cells after 72 h using a Neubauer chamber. Miltefosine was used as the positive control.