Effect of RGDechi15D on wound healing activity. (A) The wound closure was determined by the scratch assay. After the treatment, the cells were photographed using phase-contrast microscopy at 0, 24, and 48 h. (B) Quantification of wound closure. Graphic represents the wound width for each treatment, expressed as the mean ± SE of the percentage of the wound width at 24 or 48 h with respect to t = 0. The means resulted from at least three independent experiments performed in triplicate. Statistical significance was analyzed using Student’s t test, unpaired, two-sided (* p < 0.05). Blue: control; Red: RGDechi15D; Green: scrambled peptide.