Table 3.

IC₅₀ values of compounds 13–15, Econazole nitrate and Fluconazole on dermatophytes. Each value is the mean of three measurements.

	IC50 (µg/mL)
Compound	M. gypseum	M. canis	T. mentagrophytes	T. tonsurans	E. floccosum
10	1.53 ± 0.05	1.34 ± 0.02	1.38 ± 0.08	0.97 ± 0.06	1.07 ± 0.03
11	1.54 ± 0.02	1.58 ± 0.06	1.61 ± 0.10	1.89 ± 0.22	2.44 ± 0.05
12	1.55 ± 0.03	2.14 ± 0.09	1.74 ± 0.11	2.42 ± 0.15	3.80 ± 0.07
Fluconazole	18.5 ± 1.23	29.6 ± 1.84	3.53 ± 0.26	19.41 ± 0.87	0.08 ± 0.005
Econazole nitrate	0.05 ± 0.0001	0.51 ± 0.02	0.006 ± 0.0001	0.13 ± 0.008	0.47 ± 0.015