Figure 2.

Effect of ST2825 on inhibition of pro-inflammatory cytokine secretion in the supernatant of LPS-stimulated PBMC. The soluble pro-inflammatory cytokines were determined in the PBMC supernatant of HBD (n = 10). PBMC (1 × 10⁶ cells per well at a final volume of 1 mL) were cultured for 24 h under three different conditions: First, RPMI medium alone; second, LPS (30 ng/mL) and third, LPS (30 ng/mL) plus ST2825 (30 μM). Data provided in median and interquartile ranges (^Φ Kruskal-Wallis test and multiple comparisons by Dunn’s test).