Figure 5.

(a,b): The effects of EA flower extract on cell invasion of human HER2-positive breast cancer cells. EA extract inhibits cell invasion ability of SKBR3 (a) and ZR75-1 (b) cell lines by approximately 70% in comparison with their matched control cells (unexposed) (p < 0.05). Boyden chambers were used to assess cell-invasion ability of SKBR3 and ZR75-1 cell lines. Cancer cells treated for 24 h with 100 and 200 µL/mL EA plant extract showed a significant inhibition of cell invasion in both cell lines, when compared with their matched control (p < 0.05). Data are quantified by normalizing the number of invasive cells by their total number.