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. 2020 Sep 7;20(18):5089. doi: 10.3390/s20185089

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SERS measurement and PCA analysis of the captured living malignant MCF7 cells and non-malignant MCF10A cells. The SERS spectra of MCF7 (a) and MCF10A cells (b) The measured spectra were followed by Savitzky–Golay smoothing (width = 21, order = 5), background subtraction and normalization. The inset is OM images of the MCF7 and MCF10A cells, respectively. (c) Scatter plot of the score values of each Raman spectrum for PC1 and PC2 from the MCF7 (red triangles) and MCF10A (green circles); (d) Loading plot of PC1.