Figure 1.

TEER of Caco-2 cells cultured with single OA and NIC. Data in the graph are represented as percentage over the initial TEER value and given as means (n = 6) ± SEM, represented by vertical bars. Means with different letters indicate statistical significance with p < 0.05 (a, b); means with at least one common letter are not significantly different (ab), colors of the letters refer to the different treatments. TEER = transepithelial electrical resistance (Ω·cm²). (a) Cells treated with citric acid; CTR = control group; 260 = treated group with 260 μM of citric acid; 455 = treated group with 455 μM of citric acid; 651 = treated group with 651 μM of citric acid. (b) Cells treated with sorbic acid; CTR = control group; 298 = treated group with 298 μM of sorbic acid; 521 = treated group with 521 μM of sorbic acid; 745 = treated group with 745 μM of sorbic acid. (c) Cells treated with thymol; CTR = control group; 23 = treated group with 23 μM of thymol; 40 = treated group with 40 μM of thymol; 58 = treated group with 58 μM of thymol. (d) Cells treated with vanillin; CTR = control group; 13 = treated group with 13 μM of vanillin; 23 = treated group with 23 μM of vanillin; 35 = treated group with 35 μM of vanillin.