Figure 3.

(A) Inhibition of Aβ₄₂ aggregation by DCA, its derivatives, and natural sphingomyelin synthase inhibitors, as shown by incubation of 30 nM QDAβ and 30 µM Aβ with various concentrations of these compounds. (B) Estimation of EC₅₀ values from inhibition curves, in which the percent SDs of fluorescence intensities were plotted against the concentrations of these compounds.