Figure 1.

Structures of previous reported acetylcholinesterase (AChE) inhibitors 1a–f with 6-methyluracil, nitro-, and trifluoromethyl moieties [25] and herein reported AChE inhibitors 2a–c, 3, 4a,b with 6-methyluracil, quinazoline-2,4-dione and nitrile moieties. Numbering of pyrimidine ring atoms is shown.